AAOS Updates Clinical Practice Guideline to Prevent Total Hip and Knee Arthroplasty Periprosthetic Joint Infection in Patients Undergoing Dental Procedures

AAOS Updates Clinical Practice Guideline to Prevent Total Hip and Knee Arthroplasty Periprosthetic Joint Infection in Patients Undergoing Dental Procedures

Updated guideline establishes guidance based on latest in evidence-based recommendations

ROSEMONT, Ill., Dec. 17, 2024 /PRNewswire/ — The American Academy of Orthopaedic Surgeons (AAOS) issued an updated Clinical Practice Guideline (CPG) for the Prevention of Total Hip and Knee Arthroplasty Periprosthetic Joint Infection (PJI) in Patients Undergoing Dental Procedures, which replaces the previous guideline from 2012. The CPG supports patients who are scheduled for or have undergone total joint arthroplasty (TJA) and may need dental procedures by addressing antibiotic use and the timing of dental procedures before or after joint replacements, such as total knee arthroplasty (TKA) or total hip arthroplasty (THA) to help prevent infection.

(PRNewsfoto/American Academy of Orthopaedic)
(PRNewsfoto/American Academy of Orthopaedic)

To view the full guideline, click here.

“Dental procedures are believed to possibly allow bacteria to enter the bloodstream and attach themselves to hip or knee implants, potentially causing PJI in a patient,” said Yale Fillingham, MD, FAAOS, co-chair of the AAOS’ guideline development group. “PJI is one of the most devastating complications for patients following TJA, and we must do everything possible that is supported by evidence to prevent these infections. Given the large number of annual TJA procedures and that most of these patients undergo a dental cleaning at least twice a year, this CPG is relevant to nearly every TJA patient.”

THA and TKA are two of the most common surgical procedures performed worldwide. In the United States, over

1 million THAs and TKAs are performed each year, and these cases are estimated to increase by 659% and 469%, respectively, by 2060. Unfortunately, PJI is associated with increased mortality (up to 250% greater than patients who do not have PJI, along with the risk of a higher incidence of mental health disorders).

The workgroup studied the latest data to provide clinically backed evidence for orthopaedists and dentists aimed at prevention but also weighed it against potential patient harm. The updated guideline includes two limited-strength options and three consensus options. Options are developed when little or no evidence exists on a particular topic.

The group issued a limited-strength option stating that routine use of a systemic prophylactic antibiotic before a dental procedure in patients with a hip or knee replacement may not reduce the risk of a subsequent PJI.

“The committee took a close look at the data on the administration of antibiotics before a dental procedure after both hip and knee replacement to see if it mitigated the potential risk of a PJI associated with that dental procedure,” said Charles Hannon, MD, FAAOS, co-chair of the AAOS’ guideline development group. “Based on the best available data, no study found that administering antibiotics before a dental procedure changed a patient’s risk of getting a parasitic joint infection. With that said, it is important to recognize there may be other considerations that may lead a provider to prescribe antibiotics for an individual patient. This decision should be made with the patient, and the unique risks and benefits for the patient should be considered.”


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